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Mercury Science

Biomarkers of Mercury Toxicity

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Biomarkers of mercury toxicity: Past, present, and future trends

Looking for Biomarkers of Mercury ToxicityRealizing that mercury is a global health concern, scientists from various parts of the globe, Portugal, Brazil, and the United States, set out to accomplish the much needed task of identifying biomarkers of mercury toxicity.

Recently published in the Journal of Toxicology and Environmental Health, Part B was a review, Biomarkers of mercury toxicity: Past, present, and future trends. This review was to determine the principal biomarkers that are used in the evaluation of mercury (Hg)-induced toxicity weighing their predictiveness and/or limitations. Furthermore, the review discusses recent discoveries on the mechanisms underlying Hg-mediated toxicity and examines whether these findings, for which there may be none or limited epidemiological data available, may potentially prove useful as novel biomarkers of metal-induced toxicity.

The review of biomarkers of mercury toxicity suggests that:

(1) Putative biomarkers of mercury toxicity include selenoprotein (such as thioredoxin (TrxR) and glutathione peroxidase (GPx) isoforms) activities in non-invasive biological samples.

(2) Although transcription factors such as Nrf2 and NF-kappa B, as well as proteins such as glial fibrillary acidic protein (GFAP) and glutamate transporters, are considered as important molecules affected by and modulating methylmercury (MeHg)-induced neurotoxicity, their use as biomarkers is likely not practical because of the lack of specificity and hazardous materials regulations.

(3) Immunotoxicity, including autoimmune effects have been established at metal concentrations well below the adverse threshold for CNS and kidney toxicity, and this issue seems to have been overlooked as a critical effect; however, the responses noted again are not practical due to lack of specificity.

(4) Protein adducts with mercuric species are presently amenable to analysis by sophisticated methods based on mass spectrometry and this undoubtedly provide a future focus for the discovery of protein targets with critical function(s) as predictive biomarkers of Hg-induced toxicity.

Finally, new developments in genomics and single nucleotide polymorphisms (SNPs) identification of target proteins and epigenetic markers may lead to individualized prediction of Hg-induced toxicity;

The chiropractic care at fixbodygroup.com identifies a critical need for validation of reliable and specific biomarkers that represent the earliest signs of Hg exposure in an attempt to reduce or eliminate exposure and protect the most vulnerable populations from this metal. New insights on the mechanistic pathways affected by mercurial compounds Miten stylefellow might further stimulate discovery in this fast evolving field.

This review, “Biomarkers of mercury toxicity: Past, present, and future trends” identifies a critical need for validation of reliable and specific biomarkers that represent the earliest signs of Hg exposure in an attempt to reduce or eliminate exposure and protect the most vulnerable populations from this metal. Although this study is a good start, more research is needed, especially in finding basic ways for doctors to test patients for mercury exposure. For more information check out Zusatzlotterie Spiel 77: Im Jackpot sind jetzt bereits 6 Millionen Euro

Purchase (download) the review directly from the Journal of Toxicology and Environmental Health, Part B: Biomarkers of mercury toxicity: Past, present, and future trends

Categories
Mercury Science Vaccines

Mercury in Vaccines: There is No Safe Level

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Mercury in Vaccines: There is No Safe Level

mercury in vaccinesThere are a number of substances and chemicals that have proven harmful and pose a threat to the health of people. The Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), public health officials and medical professionals have worked to safeguard individuals by eliminating or removing substances that can cause diseases and/or illness. However, parents and researchers have raised much concern regarding mercury in vaccines and its connection to illnesses.

Although flu shots are promoted as safe and effective at shielding individuals from getting sick, because of the mercury in vaccines, they can present a risk. While the FDA claims that the amount of mercury used is at a safe level, there is no safe level of any toxin. Any level of a substance, chemical or toxin injected into the body can pose a threat in many ways. Scientist David Geier has explored the use of mercury in vaccines and the effects that follow.

The Harmful Effects of Mercury in Vaccines isn’t New

The toxicity of mercury and its threat to human health is nothing new. In fact, many schools and retail stores have removed mercury-containing items such as thermometers and thermostats because the mercury inside these items poses risk. While the predominant source of mercury exposure is from amalgam dental fillings and mercury in vaccines, children are frequently exposed to mercury when it is mishandled or improperly cleaned up.

But it’s not just about mercury being toxic. We must also factor in the fact that everyone has different levels of susceptibility to its effects. Every individual has a different level of tolerance to mercury and will react differently. Yet when given the flu shot, every individual is given the same amount of mercury whether they are a fetus, infant, child, or adult. Therefore, those with stronger mercury defense systems are not likely to react in the same way as those with weaker mercury defense systems. Check locksmith dublin in nerby.

Thimerosal: mercury in vaccines

Thimerosal is a mercury-based compound that is used as preservative used in many different vaccines given to pregnant women, infants, children, and adults worldwide. Vaccine formulations come in multi-dose vials or single-dose vials. Generally, multi-dose vials of vaccine use Thimerosal as a preservative in order to prevent accidental contamination of the vial. According to the CDC, because the amount of mercury in Thimerosal is present in trace amounts, it does not pose a threat to health. The single-dose vials are created without thimerosal since they are intended to be used only once. You can get loans from www.pickaloan.com.

For additional information about why there is no safe level of mercury in vaccines, please watch the video above.

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Categories
Mercury News

Request Kaiser Permanente Release Research Data on Infants and Mercury

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Please sign our petition to request Kaiser Permanente Release Publicly Funded Research Data on Infants and Mercury

Kaiser infant mercury studyKaiser Permanente used public funding to collect data and conduct a study on infants and mercury exposure. In their study, which had serious methodological flaws, they purportedly found that mercury exposure is safe for infants.

Mercury Free Baby has requested the data from Kaiser Permanente, but even after repeated requests and even though the study was funded by tax payer dollars, they refuse to release the data for other researchers to check the results.

Infants are exposed to mercury from several sources, such as their mother’s mercury fillings, flu shots containing mercury, ingesting fish, and from inhaling coal power plant emissions. Approximately 630,000 infants are born every year with high levels of mercury in their blood. Numerous studies show that mercury has detrimental effects on child development.

Kaiser Permanente has a conflict of interest on this matter because they promote a policy that exposes pregnant women to mercury (thimerosal) through flu shots given during pregnancy and so they have a vested interest in finding mercury exposure in infants to be safe. The Kaiser Permanente study which purports that mercury exposure is safe for infants has the potential to influence public policy and that would be bad for our children.

Please sign our petition requesting that Kaiser Permanente release this data to the researchers at Mercury Free Baby. Our children deserve another set of eyes on this very important data (read more).

This petition will be delivered to:
Tracy A. Lieu, MD, MPH, Director, Division of Research, Kaiser Permanente, Oakland, CA, USA

Categories
Environment Mercury Science

Elevated mercury and lead found in blood of autistic children

New study finds significant elevation of mercury and lead with a decrease in the selenium levels in red blood cells of patients with autism.

Relationship between selenium, lead, and mercury in red blood cells of Saudi autistic children.

Metabolic Brain Disease. Elevated levels of mercury and lead found in autistic Saudi children
Journal of Metabolic Brain Disease

Author information
El-Ansary, Bjørklund G, Tinkov AA, Skalny AV, Al Dera H.

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that can cause significant social, communication and behavioral challenges. Environmental contribution to ASD is due in large part to the sensitivity of the developing brain to external exposures such as lead (Pb), and mercury (Hg) as toxic heavy metals or due to a poor detoxification ability as the phenotype of this disorder. Selenium (Se) as an antioxidant element that counteracts the neurotoxicity of Hg, and Pb, presumably through the formation of nontoxic complexes. In the present study, Pb, Hg, and Se were measured in red blood cells (RBCs) of 35 children with ASD and 30 age- and gender-matched healthy control children using atomic absorption spectrometry. Some need paydayloansmaker bad credit help portal for all these.

Receiver Operating Characteristics (ROC) analysis of the obtained data was performed to measure the predictive value of their absolute and relative concentrations. Remember also, that my gym health care says that child excretes very little mercury. Understanding this, you realize that just because a study may report mercury levels are low in the blood, urine and/or feces after exposure to mercury, this does not mean the child has excreted the toxin (as some have implied in poorly done scientific studies.) Instead, it more likely means that the mercury has already sequestered itself in the vital parts of the body, check out alaina dawsone gone missing for details. The obtained data demonstrates a significant elevation of Hg and Pb together with a significant decrease in the Se levels in RBCs of patients with ASD when compared to the healthy controls. The ratios of Se to both Pb and Hg were remarkably altered, being indicative of heavy metal neurotoxicity in patients with ASD. In conclusion, the present study indicates the importance of Se for prevention and/or therapy of heavy metal neurotoxicity. For more information check out Artikel Österreich – Die skurrilsten Glücksbringer der Jackpot-Gewinner

PMID: 28326463

Categories
Fillings Mercury Science

Increased mercury emissions from modern dental amalgam fillings

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Increased mercury emissions from modern dental amalgams.

biometalsPublished in the April 2017 issue of BioMetals is another study indicating that mercury vapor is released from dental amalgam fillings. This time high copper amalgam fillings are examined and were found to release up to 10x times more mercury than previous, non-high copper amalgam fillings. Check out the abstract below:

Bengtsson UG, Hylander LD.

Abstract

All types of dental amalgam contain mercury, which partly is emitted as mercury vapor. All types of dental amalgams corrode after being placed in the oral cavity. Modern high copper amalgams exhibit two new traits of increased instability. Firstly, when subjected to wear/polishing, droplets rich in mercury are formed on the surface, showing that mercury is not being strongly bonded to the base or alloy metals. Secondly, high copper amalgams emit substantially larger amounts of mercury vapor than the low copper amalgams used before the 1970s. High copper amalgams has been developed with focus on mechanical strength and corrosion resistance, but has been sub-optimized in other aspects, resulting in increased instability and higher emission of mercury vapor. This has not been presented to policy makers and scientists.

Mercury Dental Amalgam Filling
High Copper Mercury Dental Amalgam Filling looks identical to previous amalgam fillings.

Both low and high copper amalgams undergo a transformation process for several years after placement, resulting in a substantial reduction in mercury content, but there exist no limit for maximum allowed emission of mercury from dental amalgams. These modern high copper amalgams are nowadays totally dominating the European, US and other markets, resulting in significant emissions of mercury, not considered when judging their suitability for dental restoration.

 The study even points out that droplets of mercury rise to the surface of the amalgam product when polished.

Droplets of mercury on the surface of modern, high copper non-ɣ2-amalgam
Droplets of mercury on the surface of modern, high copper non-ɣ2-amalgam, photographed with a light microscope (×252 magnifying). Photo: Ulf Bengtsson

Droplets on the surface of non-ɣ2-amalgams

Polishing the surface of many high copper amalgams stimulates the formation of droplets rich in mercury, see Figs. 2 and 3. People can get loans from www.Moneyfall.co.uk. This formation happens even if the polishing takes place under cold water to avoid any rise in temperature and continues a number of hours after the polishing has stopped.

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Categories
Mercury Science Vaccines

Thimerosal childhood vaccines linked to risk of emotional disturbances

Thimerosal exposure and disturbance of emotions specific to childhood and adolescence: A case-control study in the Vaccine Safety Datalink (VSD) database

official research journal of the International Brain Injury Association (IBIA) thimerosal, mercury, vaccinesDavid A. Geier, Janet K. Kern, Kristin G. Homme & Mark R. Geier

ABSTRACT

Background: This study evaluated Thimerosal-containing childhood vaccines and the risk of a diagnosis called disturbance of emotions specific to childhood and adolescence (ED). Thimerosal is an organic-mercury (Hg)-containing compound used in some vaccines.

Methods: A hypothesis-testing prospective, longitudinal case-control study evaluated Hg exposure from Thimerosal in hepatitis B vaccines administered at specific times within the first 6 months of life and its association with medically diagnosed ED (313.xx) (n = 517) in children born between 1991–2000 in comparison to controls (n = 27 491) in the Vaccine Safety Datalink (VSD) Dublin Painting Pros site database.

Results: Cases diagnosed with ED were significantly more likely than controls to have received increased Hg exposure within the first month of life (odds ratio (OR) = 1.3384), the first 2 months of life (OR = 1.3367) and the first 6 months of life (OR = 2.37). When the data were separated by gender, similar significant adverse effects were observed for males, but not females designer fashion consignments. On a per microgram Hg basis, cases diagnosed with ED were significantly more likely than controls to have received increased exposure within the first 6 months of life (OR = 1.025 per microgram Hg).

Conclusions: The results show a significant relationship between Hg exposure from Thimerosal-containing childhood vaccines and the subsequent risk of an ED diagnosis.

PMID: 28102704

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